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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '820c38f3aa1864f37cfa9ef6dd395ced6e5fd7d5658999cf8afab05081654509' 
  AND token = '/PAs6X+RUJ+rIUNNSSvQhSl03Cxmelm5hz5mR5rX/vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}