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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e5977c3bd5aaf613169679e5eaa93fd1af3ab4f95e013919dae49ffccfed38e' 
  AND token = '7IL3vbCfkjGCYINPKM1sm6h66SIxTe7iil5yNKU0Mak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}