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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '64a9ab4b15943f80aa114c7ca11f12e82862c490542f2be1cfd67f15d1dee58b' 
  AND token = 'rkgM5SFrAV4igBpR3WGiYRzbt0zuTdJYr1wfV85mHjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}