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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6b9ed5a716a1e1f85dc9bbc26a936661e0b3abddac34dc82a0402a574d8c7176' 
  AND token = 'E2CiiwiLUOhlWFKFYjcUMsPy8ViOoOEmHt6sUOb6TuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}