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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '039686105f2d6b6043717a6e4008db583facb1635788d957a39ec3c7d2b49c64' 
  AND token = '+cYW4agYLdO2uOpHW3xnfLyc5k+5SrwlGL2OxMcNhng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}