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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8495ad2d248a33d05354183dc2676645d4116a3fec45d8bfe6b2beb77b0f53de' 
  AND token = 'Nx0k31+AP07UguFVm8Q6xR4SVYkkRDVFKIqEkKE7CuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}