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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8cbdddf25f6bb26e32b4f97e31efdc0097bff030f2dc0919d3885e242e448b86' 
  AND token = 'gS8OdNYju5p8ctUrKfq7XISzGkbIzbc4OVtvGTfy4kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}