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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '650f035ed922765f026d4fa54973d691acfc73d70b4e06bb65f9a78b6d96ac31' 
  AND token = 'IWRWQ2Qa97+dJQ+HJlq05yNxeWFCH+zo5kw4eZVoerI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}