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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd3bdb00eb0e2975aa7cb7854a425d541debe1089c0b49f6260e32c204e37d992' 
  AND token = 'yce0BCxEGIVrPxX/sn5z0Cr+a7BY5ERDBgjqjzDVdLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}