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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a21cfa81e637f77680fd1f78446591d1e2b8968aeec76a80476fe0b839cb1bfc' 
  AND token = 'nEH2xX1s3G0+A2bvgFOH0bgbYtFIIK1WOdENQ8k7d8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}