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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7903e9c1d46971959c763b8ed9395d815bccd78f2c2c1eaec351347c22147788' 
  AND token = 'uvRI39uX49Tn9QBlE8gdlADf5rCvuQnbkH+bKVGuJ/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}