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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b0442d34435f19d926a6169e1b591f7cc7e8c0e16828ec3f59caa419be0c6199' 
  AND token = 'IvhWyIqf0NEE0WvEDMjUYR7lTXIT+Ju5DSPpWP9cP2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}