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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '614ea22b636299068eb9e4bac09bb0675b5235ae4a2c14ac4b2771d6f6c515d6' 
  AND token = 'GxxrZk6bRcs56qfi/1OEV1TdsJpjqpaEDTaekGd1a6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}