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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd4780db99cd0a7273f3fe5a969ef3219f40c27f6acc075ccea34edfed061f16a' 
  AND token = 'x2M40LJ/2Y8FNo46aiLNgsuJepn1oP4w+QmTwYhucWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}