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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46efb1f9f3cec8117cd2e3e4e10786ec521dda34b0f7e4223f44c506d7f684cd' 
  AND token = 'sBcDSC2qmHh4HPmVUV56gzkDI+098Jk2By8yvFFMrRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}