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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '57e19fd9afe16175c012957363c8f19fc2381c135da3e161ecaa3a2cea0c3a68' 
  AND token = 'eKCxN2IxMcdOdni8o08K3b1HVtmn+1ipmCNVZdeu5O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}