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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c225f989a94732700667402a25b374448705385ae79a712c9b68a8e7705b551c' 
  AND token = 'MlSZivb2Xa2Jkhxd/sF1O9raSahOSigIZ8ZuijmsFyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}