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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3b2ad69a3da7ffb91e0084f41c499622d66e27c8f6e9b6747427defbd664e4f2' 
  AND token = 'I6vqPW3oao4xxvRcd2VZoZgJmS8bfVaPELvjKzDPppw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}