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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8080d0eb9998f5af531bbd0ded6216bf7d8b0534b68b49c8f0bd3c646efa759b' 
  AND token = '8SQtxxYKB/1ZCXtzb7IWL4zZgK8lxiKL5unHZD64Pdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}