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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '17d738ede96f4e7ff5b9aa7f0769f31f4970fc0391a5ffa6861d1f1c64007844' 
  AND token = 'xAfgd+XRPArJvRqh9XdRN7+RWEJy1NdrhPvdMrCkHF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}