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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2c1fd074262f260b1e31fc6658aeda1773f966d01001d5bcc810fb0370a6d362' 
  AND token = 'o6MTOW378uYS0plOWCxLqM6hMVCAy01FDGOezfSEzh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}