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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c4782b72f5cdb6dda42a07137fcc1f187f470fbcac68f5f948cd02709d3cbc56' 
  AND token = 'WrDBwBQLisaNa33FZcfdiCxDsfUJcwirPIgLzbij8TI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}