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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4b3aa50a9cb5025792d6b06c86093e3ced58c075de786f6aeefe8a4e73f4b656' 
  AND token = 'T3GnGlgDTP02S5UpnSOLqo6oBHr55mUNQJ7faw6f7So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}