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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '50efc51a93c6e087509264d9d05b78eb78f2c7678a1b91d057703e12804fc346' 
  AND token = '/lXrMIw8JBee33f6/dhf8YRmaNALEZc34kZYhgawq7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}