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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c6f56e6e1a2de761e1b881b156d2a42f12069421b3daef4a19ddee02ab01428' 
  AND token = 'xrXwXlmoMgvVltHF/L1UKTNwfwKN44djtabKFOd9enc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}