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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed45374c75435fbaad6ef55bef33803b06af639dab04b55346b218cc9e948946' 
  AND token = 'wPMF8YGptdWPhABQ57+IgHZLmZ2cs0Oi4C76Wn8HO6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}