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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7490fd45765505eb874de9b86e5b59772b8ebe2b52d7740a3fddf54c5b0f5360' 
  AND token = 'w8kw2WwC0lVT4OXzScoNE5V5GgM+h12RLJFmyEIBT5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}