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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e59e922e02973982d5ad32f11e309cbce12e3bf6286be486ec04da2f449f8203' 
  AND token = 'aERgR7IgZiuv2yhSJodlYCUFkml2RxWaJls5my2uRNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}