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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10cb3ba2116d49b0ba123a90f1f9d0e84ff3d870ebc1d94dd053c5dce05f1135' 
  AND token = '+6QpQuIHqTOmZlpAcgE7bhqtE/LSkT0UEjtnzhExu1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}