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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e5883d31e86a16c7e53267a34d2d16f5c5f6f3f98df6500d1a01d9e1925e98de' 
  AND token = 'HNIJFZBKg6rfu1YbEH4ntaVdIFmHg6OALfsAf0kfW0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}