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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3cface4fd2b8a0bbc1adaab20e0543f2a0f93e9c4c9031dbf660dd8c3ce396cf' 
  AND token = 'eD3tTmIjw45kOPQD2wNev2vSUJs/cMsDaAjBuhzZt3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}