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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'bf23efb1edd0a18f92fc9c69fa82242b121208f2f4038c99ca6a09a2547d9edf' 
  AND token = 'TiPchhV3+UyxcY8MjyZDSUkHaJNUlkINdvhZ7L4ZCWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}