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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c23b5e8eebe892c84cb9da8ad8dcf46ea5d50a7adf4c9dc269e5873b55816808' 
  AND token = 'QGe/u/m1sXZFZyUSIMGZ7Sp2O3+Gj97s1t8DimwhdAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}