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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7f3786d7ed9be892dc883f2f3b74dc6372bc43ee1a779a394d2effac38e71607' 
  AND token = 'ZuZ2+JXytL4FOgmBWf4XpV2pU42sDL8u8GkhWLl82A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}