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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '286bfcaf41ab3fa54afaf8c48c49aecd9a32146dfe4d0f6762ba358b259eb70a' 
  AND token = 'sWw8iC4LjSPwuQKEY2EZeOLzXE29WWRFuq7tw9I6vEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}