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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '443005ad7c8236a6d81c3d810f8b44500a2f21584a15d4416d73937d9454cafd' 
  AND token = 'Mi9d9ySXUU52eFisrlg+/eBexL6x7FsM8spdqLMElsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}