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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '327f377e94ece625be378866d39833ce2131f3a294bf7a7d171596186a4bc3f9' 
  AND token = 'rKRqydxokdh45OOsdUd9c3gO0Dgs2oJpbjVbhWfOUV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}