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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '442353d5d2ec182662d9b842a7927809ad72f0d4eb19bb59a9ee3541384dab5a' 
  AND token = 'pmrEN5OtWxJHIwso+X+gNOVpAUQsguoJ2EbN1GMU0BY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}