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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7c4a5746fddcaedd92366426beb34d68abb99e2e9eeb286bff204b03653da664' 
  AND token = 'MC07MY3u+WznbA7iaXtYohjs4zIVVFZvhRkj/LU4ASc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}