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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '50d52d89d1771e2ab22036c03d1b6631c16d2e4b2b8e8638d8801bf622367f8b' 
  AND token = 'hRE2aIZl6Pn7AQXTQasp2y2ik+Mt6kaAD2skqgDiVEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}