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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b25845086b15db4742cfe1f12b758fac4992be300856a7e01bd4d3f93d0960c3' 
  AND token = 'R+Wu7ARihIuRmMyIMlOJeYTxaNTIsheKQV8yxNunneo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}