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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21b06be678ca93c6ba56a19e0d7c6216ff45e0f571672afb2956cf3ca8e6722c' 
  AND token = '+GicUarcN/8niqUk66HPt0IN2VaH2Opzt9ek9IhixEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}