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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '61d74d222570e26aabf6df19ab01cad59d531972ae9b8db28c14a46339135d59' 
  AND token = 'JXABXntIJtuXFJjm++dEaRJKtLmkFeK3n0sWY/vtL2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}