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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0508f5bffa774c69ff7a69f74be0e8f2656a529fbe7fbfe1232601fb05d54f0d' 
  AND token = 'S0v8lExeCMaHxyaGIfxJwhh61yHuaUK5IdVFm3+mJkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}