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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42b0117cc0e59fd13654e50f04a2090d2893a36881409ffec7189cb039ae4d65' 
  AND token = 'B4cRApvpA6+aWQLq/Dp63feyrv5HI4Led7vGXgDBHAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}