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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f4cf5d528b6586ca3e4b80b90ac3f63327da1abc4230593899a5fde6dacd010' 
  AND token = 'JkmtP47fMBTMcqXFwfbpv3GDWlW5UinQ+giS6I6ng3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}