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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6cedb66656746cf61181afce73a8789746aed8fb48d1f21cdc8344af38b0247a' 
  AND token = 'i54UutoZlpwk53guW0c641XTmbngBYl5E/POVgWaZkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}