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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cc049554e6cb4d572a31ac8c3b7fffcdf6d6e4cf3c7e1df57a16f39587964381' 
  AND token = 'U7U55B+PPn6ORuLmyBIpXw9OjXyXRaBfIOVELui58Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}