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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21acbf9aa6a5ad14c60b35765a425ea20e77f2fcd6c15a3e7d2e66952307291b' 
  AND token = '/fjdB8qWj37GuH7SBE5TOBShHy23b5ZyinH1Hblsrr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}