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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '59612e16fe109f50b0a355a93d6a50c38818e32f1396b4ff6b65262dba43a2cf' 
  AND token = 'F1H2MFZOX+MjMfOpFMDE/2kucb9fjYxq2wFf+j1U5Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}